Choosing The Greater Philadelphia Region for Business Expansion

For companies planning their next move, business expansion in the Greater Philadelphia region involves far more than selecting a new location. Fortunately, practical support for relocation, market entry, and long-term growth is available at every stage of the decision.

The Greater Philadelphia Growth Partnership and regional economic development partners all provide businesses with valuable resources, helping organizations evaluate opportunities and turn them into workable plans.

Reaching Markets at Any Size

Expansion teams comparing East Coast markets typically measure three key areas: reach, labor, and cost.

A single day’s drive from the Greater Philadelphia region covers 40% of the […]

TerraPower Isotopes Joins Greater Philadelphia’s Radiopharmaceutical & Nuclear Medicine Ecosystem

TerraPower Isotopes has announced a $450 million investment to establish a 250,000-square-foot facility at Greater Philadelphia’s Bellwether District. This new manufacturing facility is dedicated to the production of cancer-fighting radioisotopes, further solidifying the region’s status as a global hub for life sciences. The company joins an ecosystem of radiopharmaceutical and nuclear medicine organizations already operating within the tri-state area.

The Select Greater Philadelphia team at the Chamber of Commerce for Greater Philadelphia supported TerraPower Isotopes throughout the site selection process, highlighting the region’s competitive advantages for large-scale clinical and manufacturing investments. The search was conducted […]

Navigating the Greater Philadelphia Economic Landscape: Insights from Business Sentiment Reports

Understanding the nuances of the economic environment is crucial for any successful business. For business owners in Southeastern Pennsylvania and Philadelphia, The Chamber of Commerce for Greater Philadelphia‘s in-depth business sentiment reports, conducted as part of the Pennsylvania Department of Community & Economic Development’s “Engage!” Initiative, provide a glimpse into current market conditions.

For the past seven years, the Chamber has been conducting a comprehensive sentiment analysis of data collected by the region’s local partners across Berks, Bucks, Chester, Delaware, Montgomery, and Philadelphia counties. By proactively listening […]

New International Flights from PHL Connects More Global Markets and Talent to the Region

Philadelphia International Airport (PHL) kicked off summer 2025 with exciting route expansions. American Airlines launched daily nonstop service from PHL to Edinburgh, Scotland and Milan, Italy, beginning May 23, 2025, alongside the return of seasonal service to Copenhagen, Naples, and Nice. Also, Aeroméxico established year-round daily nonstop flights between PHL and Mexico City (MEX) starting June 5, 2025, marking the first direct link since 2019.

Philadelphia International Airport’s new destinations are not just new routes – it’s a new opportunity for Greater Philadelphia to elevate the region’s international visibility, support business attraction in high‑growth industries, and foster inclusive regional economic growth.

Companies often mention […]

Discovery Starts with The Wistar Institute’s Cellular Biologist Michela Perego, Ph.D.

Posing for a photo in the hallway at The Wistar Institute dressed in a white lab coat and smiling at a camera, cellular biologist Michela Perego, Ph.D., shared a little secret: Working as a scientist in a lab isn’t as glamorous as it appears on TV. 

As Perego explained, the long hours spent in the lab can be draining, and the perseverance required to keep moving forward amid setbacks can be frustrating. But despite what Hollywood’s depictions may gloss over, Perego said, in her opinion, working as a […]

‘Stay for Philly’ – New Talent Attraction Campaign Highlights Top Reasons to Live and Work in Greater Philadelphia

The Chamber of Commerce for Greater Philadelphia (the Chamber) has launched a new regional talent attraction campaign – Stay for Philly. This initiative builds on the region’s renowned tourism campaign, ‘Come for Philadelphia, Stay for Philly,’ but shifts the focus to transforming top talent into permanent residents.

Developed in partnership with Visit Philadelphia, the Chamber’s Stay for Philly campaign also draws inspiration […]

Philadelphia’s 2026 Events: A Catalyst for Long-Term Economic Growth

The Greater Philadelphia region is gearing up for a momentous 2026 when Philadelphia will host multiple major events, including six FIFA World Cup matches, the MLB 2026 All-Star Game, and the nation’s semi-quincentennial celebrations. These events are expected to bring an unprecedented number of visitors and significant economic impact to the region.

While local government leaders and the Greater Philadelphia business community are focused on ensuring the region is ready for 2026, the Chamber of Commerce for Greater Philadelphia (the […]

Greater Philadelphia Life Sciences Industry Hub Poised for Success in 2025

The Greater Philadelphia region continues to solidify its position as a nationally leading life science hub, thanks to its dense network of top-tier incubators and prime location, which topped the priority list for both life science real estate investors and companies in the past year and is listed as a life science trend to watch for 2025.

A new report by JLL on life science real estate trends to watch in 2025 affirms the growing appeal for collaborative lab spaces […]

Greater Philadelphia’s Economic Forecast 2025: Insights and Opportunities on Region’s Horizon

The Chamber of Commerce for Greater Philadelphia (the Chamber) hosted its annual State of the Economy event on January 9, 2025, bringing together the region’s business community, including Chamber members and investors, to hear from local economists and leaders on industry insights, trends, and growth opportunities expected to drive the region’s economic performance in the year ahead.

The goal of the annual event, supported this year by title sponsor and Chamber member Firstrust Bank, is to help Greater Philadelphia businesses make informed decisions. It

2023-24 Engage! Interviews Summary Report: Employer Opportunities & Challenges in Philadelphia

Select Greater Philadelphia (Select) is excited to present our report summarizing the outcomes of the 2023-2024 Engage! Interview Initiative for Philadelphia.

Drawing from data provided by the Pennsylvania Department of Community & Economic Development (PA DCED) through its 2023-2024 “Engage!” program, for which the Chamber is a supporting partner, the Select team analyzed insights from 87 interviews with business owners in Philadelphia County during the 2023-2024 fiscal year. This comprehensive report compares the findings from Philadelphia businesses to regional data, serving as a tool to help businesses benchmark their engagement and explore […]

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