Philadelphia County

Our Region’s Vibrant Urban Hub

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Why Companies and Talent Choose Philadelphia

If you are considering locating or expanding in the City of Philadelphia – the largest in the Commonwealth of Pennsylvania and the urban core of Greater Philadelphia  – you will benefit from the partnership between the City of Philadelphia Department of Commerce and the Chamber of Commerce for Greater Philadelphia. Together, we attract international and domestic companies, support the expansion of businesses already located here, and convene workforce partners for job opportunities across all business sectors. Benefit from our concierge-level service – from your first visit to your ribbon cutting and beyond. Philadelphia is the premier place to start, stay, and grow.

GLG expanded to Philadelphia to tap into the city’s incredible talent and be close to leading local clients. Not to mention to be part of Philly’s incomparable culture, which energizes our work each and every day. Our Philadelphia team immediately became a vital part of GLG’s regional and global strategy – and we’re thrilled to continue investing in the one-of-a-kind city that we now call home.”
– Cindy Floyd, General Manager Americas Public Markets, GLG

Philadelphia County Map

Leading Life Science Industry

The City of Philadelphia is the center of the region’s globally recognized life sciences ecosystem and leadership in gene therapy, cell therapy, and digital health. Known as being the Birthplace of Cell and Gene Therapy, numerous life science companies and research institutions are in the City of Philadelphia, some of which include Children’s Hospital of Philadelphia, Coriell Institute, Christiana Care Gene Editing Institute, GSK, Jazz Pharmaceuticals, Jefferson Health, University of Pennsylvania Perelman School of Medicine, Spark Therapeutics, Temple University, The Wistar Institute and WuXi AppTec.

Additionally, in a watershed moment for Philadelphia’s booming life sciences industry, Drs. Katalin Karikó and Drew Weissman, who made significant discoveries at the University of Pennsylvania, were jointly awarded the 2023 Nobel Prize in Physiology or Medicine for their work on mRNA technology.

“The support from the city’s Department of Commerce and the Director of Life Sciences provides valuable resources and assistance, helping companies like ours navigate the complex landscape of the biotech industry. The city of Philadelphia also provides access to innovative business solutions that amplify growth opportunities and foster collaboration with other industry players. Philadelphia’s commitment to nurturing its life sciences sector is clearly paying off, making it an attractive location for companies like BioAnalysis to prosper and contribute to the advancement of biotechnology.”
– Lake N. Paul, Ph.D., Founder, Bioanalysis, LLC. (March 2024)

Thriving Tech Industry

Thriving Tech Industry

The City of Philadelphia is known for being a thriving tech industry hub that attracts talent and investment. A quarter of all new jobs in the city are in tech, spanning key segments such as B2B, software-as-a-service, digital health, biotech, fintech, and social entrepreneurship. This world-class innovation ecosystem is powered by forward-looking industry leaders such as Comcast, as well as numerous successful startups like GoPuff and dbt Labs, fueling the region’s consistent ranking among the top five most active regions nationally for venture deals.

Infrastructure and Transportation

The City is located within a day’s drive of 70 percent of the U.S. and Canadian population, with 1-76 and 1-95 highway access, and within a two-hour flight to more than 60 percent of the U.S. population. Philadelphia International Airport is American Airlines’ Transatlantic Hub and offers 320+ daily departures and 120+ nonstop destinations, including 30 international.

Amtrak 30th Street Station is the third-busiest train station in the U.S., with convenient access throughout the Northeast Corridor and beyond. The Port of Philadelphia also provides a critical link in our nation’s supply chains.

SEPTA, the nation’s fifth-largest regional transit system, provides public transit access that includes subways, buses, trolleys, and suburban rail lines.

The ease of getting around in the City is also a breeze thanks to founder William Penn’s intentional decision to design Philadelphia as a grid system. Today, Philadelphia is ranked fifth in the U.S. for walkability and bikeability. The City’s Indego bike stations and network of bike lanes are spread around the City, not just downtown.

Philadelphia County Infrastructure and Transportation
Commercial Real Estate

Commercial Real Estate

The City of Philadelphia has built an infrastructure for innovation, with state-of-the-art commercial real estate corridors and innovation sites designed for collaboration and discovery. We also offer the lowest office rental rates among the top 10 U.S. metros. This property search tool helps you identify available commercial space. A few examples are listed below.

Science Center & uCity Square

Science Center & uCity Square

Largest urban science park in the U.S., connecting universities, research organizations, and the private sector.

Pennovation Works

Pennovation Works

A blend of office, lab, production garage, tech-transfer, and incubator spaces.

Schuylkill Yards

Schuylkill Yards

Six university-adjacent towers offering labs, offices, and residences.

Navy Yard

R&D, office, and industrial complex home to 130 companies and the U.S. Navy.

Bellwether District

Bellwether District

A state-of-the-art redevelopment campus for life sciences, e-commerce, and logistics.

Education and Workforce icon

Education and Workforce

Philadelphia’s colleges and universities contribute significantly to the city’s workforce by providing education, fostering innovation, and producing skilled professionals across various domains. Their impact extends beyond campus boundaries, shaping the future of the city and its residents. Among the colleges and universities in the city are Chestnut Hill, Curtis Institute of Music, Drexel, Haverford, Holy Family, LaSalle, Lincoln, Moore College of Art & Design, Peirce, Saint Joseph’s, Strayer, Temple, Thomas Jefferson, University of the Arts, University of Pennsylvania, and Walnut Hill College.

Quality of Life

Quality of Life

“Philadelphia” means “Brotherly Love.” We are a welcoming and diverse city that is home to 1.6 million residents. In the City, you will find a world-class destination abundant in historical and cultural attractions and an exceptional quality of life where your team will want to live and work. Philadelphia is all about the people who live here. The city’s diverse population of talented, innovative people are fueled with passion and a spirit of invention. We are a city of neighborhoods, each with its own unique set of restaurants, murals, shops, customs, and experiences inspired by cultures from around the globe.

From Parks to Trails: Open Spaces Abound

From Parks to Trails: Open Spaces Abound

Philadelphia’s vibrant urban landscape offers ample opportunities to enjoy the great outdoors, and four distinct seasons create endless recreational opportunities. Fairmount Park, the most extensive urban park system in the country with 9,600 acres and 63 parks, stands out as a crown jewel complemented by more than 150 permanent parks, playgrounds, and seasonal pop-up gardens.

Savor the City: Philadelphia’s Vibrant Food Culture

Savor the City: Philadelphia’s Vibrant Food Culture

Philadelphia’s dining scene is exceptional, with a roster of renowned chefs and restaurateurs including a whole host of James Beard Award winners (2023 recipients Chutatip “Nok” Suntaranon and Ellen Yin, Stephen Starr, Michael Solomonov, Greg Vernick, and Marc Vetri, to name a few), a wide range of ethnic and global cuisines, and an abundance of only-in-Philadelphia flavors. Visitors and residents alike can enjoy a variety of meals and shop for specialty food items at destinations such as our historic Reading Terminal Market, South 9th Street Italian Market, Chinatown, and newly established district, Africatown.

Sights and Sounds: Philadelphia’s Arts and Culture

Sights and Sounds: Philadelphia’s Arts and Culture

You can experience Philadelphia’s rich arts and culture throughout our many neighborhoods. From the vibrant murals dotting the city through Mural Arts Philadelphia’s public art programs, to taking a stroll down the Avenue of the Arts and the Ben Franklin Parkway. There you will find The Philadelphia Museum of Art, The Barnes Foundation, The Rodin Museum, The Academy of Natural Sciences of Drexel University, The Franklin Institute, The African American Museum, The Museum of the American Revolution, The National Constitution Center, and The Weitzman National Museum of American Jewish History.

Score Big: Philadelphia's Spirited Sports Community

Score Big: Philadelphia’s Spirited Sports Community

Philadelphia pulsates with unwavering sports fervor. It is one of a small number of U.S. cities with all four major professional sports leagues within its city limits, creating a convergence of spirited fandom and unadulterated loyalty that underscores its identity as the City of Brotherly Love. Philadelphia’s passionate fan base extends to cheering on exciting college teams, and its steadfast local allegiance carries off the field, connecting people from diverse backgrounds and every neighborhood to share in the triumphs and tribulations of our beloved home teams. In 2026, Philadelphia’s passion for sports will be broadcast around the globe as the City will be one of the host cities for the FIFA World Cup.

Be Part of History: A City of Firsts

Be Part of History: A City of Firsts

Founded in 1682 by William Penn (the namesake of the Commonwealth of Pennsylvania), the City of Philadelphia is globally recognized for its rich history. We are the Birthplace of America, where the Declaration of Independence was written, and where the Constitution of the United States was drafted and signed, establishing the government of the United States. We are also home to the Liberty Bell, a national symbol of freedom and a historical landmark.

In addition to being the nation’s first capital, the City of Philadelphia is home to many more U.S. firsts, including the Birthplace of American Medicine and the Birthplace of Cell and Gene Therapy, and is an inspiration for future innovation.